Compile Data Set for Download or QSAR
maximum 50k data
Found 116 of ic50 data for polymerid = 2341,2343,5433,5434
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23251(1,2,5-Thiadiazole, TDA1 | 4-hydroxy-1,2,5-thiadiaz...)
Affinity DataKi:  290nM ΔG°:  -8.91kcal/mole IC50:  140nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23232(1,2,5-oxadiazole, OXD1 | 4-hydroxy-1,2,5-oxadiazol...)
Affinity DataKi:  210nM ΔG°:  -9.10kcal/mole IC50:  650nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23242(1,2(1,5)-Isoxazole, IOA1 | 3-hydroxy-1,2-oxazole-4...)
Affinity DataKi:  470nM ΔG°:  -8.63kcal/mole IC50:  1.10E+3nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)
Affinity DataIC50:  1.75E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  2.03E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  2.64E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)
Affinity DataIC50:  2.66E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23227(Oxamic acid derivative, 5 | [(4-{2-[(5-hydroxy-2-{...)
Affinity DataIC50:  3.13E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  3.97E+3nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23227(Oxamic acid derivative, 5 | [(4-{2-[(5-hydroxy-2-{...)
Affinity DataIC50:  6.76E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  6.90E+3nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23228(Oxamic acid derivative, 6 | [(2-cyano-4-{2-[(5-hyd...)
Affinity DataIC50:  8.25E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93303(Oxamic Acid/Ester, 21)
Affinity DataIC50:  1.40E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23243(1,2(1,5)-Isoxazole, IOA2 | 4-hydroxy-1,2-oxazole-3...)
Affinity DataIC50:  1.60E+4nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93300(Oxamic Acid/Ester, 18)
Affinity DataIC50:  2.00E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93303(Oxamic Acid/Ester, 21)
Affinity DataIC50:  2.50E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93307(Oxamic Acid/Ester, 25)
Affinity DataIC50:  3.10E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93309(Oxamic Acid/Ester, 27)
Affinity DataIC50:  3.20E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93318(Oxamic Acid/Ester, 36)
Affinity DataIC50:  3.50E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93323(Oxamic Acid/Ester, 41)
Affinity DataIC50:  4.10E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93315(Oxamic Acid/Ester, 33)
Affinity DataIC50:  4.30E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93299(Oxamic Acid/Ester, 17)
Affinity DataIC50:  4.30E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93307(Oxamic Acid/Ester, 25)
Affinity DataIC50:  4.30E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93301(Oxamic Acid/Ester, 19)
Affinity DataIC50:  4.60E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93305(Oxamic Acid/Ester, 23)
Affinity DataIC50:  4.70E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23224(7-{[4-(formamidoformic acid)-3-methoxyphenyl]metho...)
Affinity DataIC50:  4.83E+4nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93324(Oxamic Acid/Ester, 42)
Affinity DataIC50:  5.10E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93302(Oxamic Acid/Ester, 20)
Affinity DataIC50:  5.90E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93300(Oxamic Acid/Ester, 18)
Affinity DataIC50:  5.90E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23250(1,2(1,5)-Isoxazole, IOA9 | 4-hydroxy-1,2-oxazole-3...)
Affinity DataIC50:  8.10E+4nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23228(Oxamic acid derivative, 6 | [(2-cyano-4-{2-[(5-hyd...)
Affinity DataIC50:  8.69E+4nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23224(7-{[4-(formamidoformic acid)-3-methoxyphenyl]metho...)
Affinity DataIC50:  8.73E+4nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93323(Oxamic Acid/Ester, 41)
Affinity DataIC50:  8.80E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93308(Oxamic Acid/Ester, 26)
Affinity DataIC50:  8.80E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM93318(Oxamic Acid/Ester, 36)
Affinity DataIC50:  9.00E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23222(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Affinity DataIC50:  9.25E+4nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23222(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Affinity DataIC50:  9.44E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM93291(Oxamic Acid/Ester, 7)
Affinity DataIC50:  9.79E+4nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23258(1H-1,2,3-triazole-5-carboxylic acid | Triazole, TR...)
Affinity DataIC50:  9.80E+4nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23255(5-hydroxy-2-methyl-2H-1,2,3-triazole-4-carboxylic ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23257(2-benzyl-5-hydroxy-2H-1,2,3-triazole-4-carboxylic ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23244(1,2(1,5)-Isoxazole, IOA3 | 3-hydroxy-5-methyl-1,2-...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23245(1,2(1,5)-Isoxazole, IOA4 | 2-methyl-3-oxo-2,3-dihy...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23246(1,2(1,5)-Isoxazole, IOA5 | 3-methoxy-1,2-oxazole-4...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23247(1,2(1,5)-Isoxazole, IOA6 | ethyl 3-hydroxy-1,2-oxa...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23248(1,2(1,5)-Isoxazole, IOA7 | methyl 5-hydroxy-3-meth...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23249(1,2(1,5)-Isoxazole, IOA8 | ethyl 5-hydroxy-1,2-oxa...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23252(1,2,5-Thiadiazole, TDA2 | 4-amino-1,2,5-thiadiazol...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23256(1-benzyl-4-hydroxy-1H-1,2,3-triazole-5-carboxylic ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23253(1,2,5-Thiadiazole, TDA3 | 4-methoxy-1,2,5-thiadiaz...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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